Minimal model assessment of hepatic insulin extraction during an oral test from standard insulin kinetic parameters.

@article{Campioni2009MinimalMA,
  title={Minimal model assessment of hepatic insulin extraction during an oral test from standard insulin kinetic parameters.},
  author={Marco Campioni and Gianna Toffolo and Rabeya Basu and Robert A. Rizza and Claudio Cobelli},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2009},
  volume={297 4},
  pages={E941-8}
}
In this article, a first aim was to develop a minimal modeling approach to noninvasively assess hepatic insulin extraction in 204 healthy subjects studied with a standard meal by coupling the already available meal C-peptide minimal model with a new insulin model. The ingredients of this model are posthepatic IDR, which in turn is described in terms of… CONTINUE READING