Minimal-invasive magnetic heating of tumors does not alter intra-tumoral nanoparticle accumulation, allowing for repeated therapy sessions: an in vivo study in mice.

@article{Kettering2011MinimalinvasiveMH,
  title={Minimal-invasive magnetic heating of tumors does not alter intra-tumoral nanoparticle accumulation, allowing for repeated therapy sessions: an in vivo study in mice.},
  author={Melanie Kettering and H. -Peter Richter and Frank Wiekhorst and Sibylle Bremer-Streck and Lutz Trahms and Werner A. Kaiser and I. Hilger},
  journal={Nanotechnology},
  year={2011},
  volume={22 50},
  pages={505102}
}
Localized magnetic heating treatments (hyperthermia, thermal ablation) using superparamagnetic iron oxide nanoparticles (MNPs) continue to be an active area of cancer research. For generating the appropriate heat to sufficiently target cell destruction, adequate MNP concentrations need to be accumulated into tumors. Furthermore, the knowledge of MNP bio… CONTINUE READING