Minimal cardiopulmonary bypass attenuates neutrophil activation and cytokine release in coronary artery bypass grafting

@article{Ohata2007MinimalCB,
  title={Minimal cardiopulmonary bypass attenuates neutrophil activation and cytokine release in coronary artery bypass grafting},
  author={Toshihiro Ohata and Masataka Mitsuno and Mitsuhiro Yamamura and Hiroe Tanaka and Yasuhiko Kobayashi and Masaaki Ryomoto and Yoshiteru Yoshioka and Yuji Miyamoto},
  journal={Journal of Artificial Organs},
  year={2007},
  volume={10},
  pages={92-95}
}
The minimal cardiopulmonary bypass (mini-CPB) circuit, a closed system with neither cardiotomy suction nor an open venous reservoir and thus no air–blood interface, reportedly reduces blood loss and inflammatory reactions associated with coronary bypass surgery. We evaluated the inflammatory reactions in patients in whom coronary bypass operations were performed with conventional CPB or mini-CPB (n = 15 each). Interleukin (IL)-6, IL-8, and neutrophil elastase levels; the neutrophil count; and… CONTINUE READING
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