Minimal breast cancer: evaluation of histology and biological marker expression

  title={Minimal breast cancer: evaluation of histology and biological marker expression},
  author={Edwin A Dublin and Rosemary R. Millis and P. Smith and Linda Bobrow},
  journal={British Journal of Cancer},
  pages={1608 - 1616}
SummaryNinety-eight minimal breast cancers (MBCs) diagnosed between 1975 and 1990, and all originally considered to be invasive were found, on review, to form three groups: (a) 28 predominantly invasive carcinomas ≤10 mm (‘predominant invasive’); (b) 48 predominantly ductal carcinoma in situ (DCIS) lesions with definite foci of invasion each ≤10 mm (‘predominant DCIS’); and (c) 22 DCIS without evidence of invasion (‘pure DCIS’). Tumour histology and immunohistochemical expression of Ki-67, c… CONTINUE READING


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