Minimal Experience Required for Immediate-Early Gene Induction in Zebra Finch Neostriatum

@article{Kruse2000MinimalER,
  title={Minimal Experience Required for Immediate-Early Gene Induction in Zebra Finch Neostriatum},
  author={Amy A. Kruse and Roy Stripling and David F. Clayton},
  journal={Neurobiology of Learning and Memory},
  year={2000},
  volume={74},
  pages={179-184}
}
We show that a single presentation of a zebra finch song, 2 s in duration, will induce an "immediate-early gene" response in the caudomedial neostriatum of zebra finches (Poephila guttata). Repetition of this stimulus 10 times is sufficient to induce a maximal increase in RNA and protein, detected 30 and 90 min later respectively. Thus very brief stimuli can set in motion a slow genomic process in the brain which takes hours to resolve. Immediate-early gene function is often considered in the… CONTINUE READING

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