Minichromosome maintenance protein expression in benign nevi, dysplastic nevi, melanoma, and cutaneous melanoma metastases.

@article{Boyd2008MinichromosomeMP,
  title={Minichromosome maintenance protein expression in benign nevi, dysplastic nevi, melanoma, and cutaneous melanoma metastases.},
  author={Alan S Boyd and Bashar Shakhtour and Yu Shyr},
  journal={Journal of the American Academy of Dermatology},
  year={2008},
  volume={58 5},
  pages={750-4}
}
BACKGROUND Minichromosome maintenance (MCM) proteins are a recently elucidated group of polypeptides intimately involved in DNA replication and appreciable only in cycling cells. In other organ systems their expression has proven more prognostically useful than cell proliferation markers such as Ki-67 and proliferating cell nuclear antigen. To date, the evaluation of MCM proteins in melanocytic neoplasms has not been undertaken. OBJECTIVE We sought to determine whether MCM protein 2 (the most… CONTINUE READING

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