Miniaturisation of a capillary electrophoresis microchip for the sensing of endocrine disruptors.

Abstract

Although capillary electrophoresis amperometric detector (CE-AD) involving double-T microchannel configuration is a powerful analytical tool in terms of sensitivity and selectivity, its long microchannel configuration hinders further miniaturisation. Therefore a twisted CE microchannel configuration was used in the present study to fabricate CE-AD devices for detection of endocrine disruptors. The analyte separation time varied slightly for the twisted microchannel structure, whereas the detector sensitivities were similar for the two configurations. The conventional indium tin oxide amperometric detector in the device with twisted microchannel configuration was later modified with Prussian blue to enhance the sensitivity of detection.

DOI: 10.1049/iet-nbt.2010.0006

Cite this paper

@article{Ha2010MiniaturisationOA, title={Miniaturisation of a capillary electrophoresis microchip for the sensing of endocrine disruptors.}, author={K. Ha and G-S Joo and Sushant K. Jha and I S Yeon and Y-S Kim}, journal={IET nanobiotechnology}, year={2010}, volume={4 4}, pages={103-8} }