Mini-review: gephyrin, a major postsynaptic protein of GABAergic synapses.

@article{SassoPognetto2000MinireviewGA,
  title={Mini-review: gephyrin, a major postsynaptic protein of GABAergic synapses.},
  author={Marco Sasso{\`e}-Pognetto and Jean Marc Fritschy},
  journal={The European journal of neuroscience},
  year={2000},
  volume={12 7},
  pages={
          2205-10
        }
}
gamma-aminobutyric acid type A (GABAA) receptors are located at the majority of inhibitory synapses in the mammalian brain. However, the mechanisms by which GABAA receptor subunits are targeted to, and clustered in, the postsynaptic membrane are poorly understood. Recent studies have demonstrated that gephyrin, a protein first identified as a component of the glycine receptor (GlyR) complex, is colocalized with several subtypes of GABAA receptors and is involved in the stabilization of… CONTINUE READING
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