Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy.

@article{Zhao2012MineralocorticoidRI,
  title={Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy.},
  author={Min Zhao and Isabelle C{\'e}l{\'e}rier and Elodie Bousquet and J Jeanny and Laurent Jonet and Mich{\'e}le Savoldelli and Olivier Offret and Antoine Curan and Nicolette Farman and Fr{\'e}d{\'e}ric Jaisser and Francine B{\'e}har-Cohen},
  journal={The Journal of clinical investigation},
  year={2012},
  volume={122 7},
  pages={2672-9}
}
Central serous chorioretinopathy (CSCR) is a vision-threatening eye disease with no validated treatment and unknown pathogeny. In CSCR, dilation and leakage of choroid vessels underneath the retina cause subretinal fluid accumulation and retinal detachment. Because glucocorticoids induce and aggravate CSCR and are known to bind to the mineralocorticoid receptor (MR), CSCR may be related to inappropriate MR activation. Our aim was to assess the effect of MR activation on rat choroidal… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 12 times over the past 90 days. VIEW TWEETS
73 Citations
40 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 73 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 40 references

Epidermal growth factor receptor mediates the vascular dysfunction but not the remodeling induced by aldosterone / salt

  • S Messaoudi, F Azibani, C Delcayre, F Jaisser
  • 2011

Similar Papers

Loading similar papers…