• DOI:10.1152/ajpregu.00434.2013
Corpus ID: 27585846

Mineralocorticoid receptor in the NTS stimulates saline intake during fourth ventricular infusions of aldosterone.

@article{Koneru2014MineralocorticoidRI,
  title={Mineralocorticoid receptor in the NTS stimulates saline intake during fourth ventricular infusions of aldosterone.},
  author={Bhuvaneswari Koneru and C. Bathina and Brandon H. Cherry and S. Mifflin},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2014},
  volume={306 1},
  pages={
          R61-6
        }
}

• Bhuvaneswari Koneru, C. Bathina, +1 author S. Mifflin
• Published 2014
• Biology, Medicine
• American journal of physiology. Regulatory, integrative and comparative physiology

The purpose of this study was to determine whether neurons within the nucleus tractus solitarius (NTS) that express the mineralocorticoid receptor (MR) play a role in aldosterone stimulation of salt intake. Adult Wistar-Kyoto (WKY) rats received microinjections into the NTS of a short-hairpin RNA (shRNA) for the MR, to site specifically reduce levels of the MR by RNA interference (shRNA; n = 9) or scrambled RNA as a control (scRNA; n = 8). After injection of the viral construct, aldosterone… Expand

View on PubMed

europepmc.org

Save to Library

Create Alert

Cite

Launch Research Feed