Mineralocorticoid receptor, the main player in aldosterone-induced large artery stiffness.


A ldosterone, a key hormone in the control of sodium and potassium balance, regulates extracellular volume and blood pressure. In the kidney, aldosterone, released by adrenal glomerulosa in response to angiotensin II, high potassium levels , and adrenocorticotropic hormone, classically acts through the mineralocorticoid receptor (MR), a ligand-activated… (More)
DOI: 10.1161/HYPERTENSIONAHA.113.02581


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