Mineralocorticoid Receptor–Mediated Vascular Insulin Resistance

@article{Bender2013MineralocorticoidRV,
  title={Mineralocorticoid Receptor–Mediated Vascular Insulin Resistance},
  author={S. Bender and A. Mcgraw and I. Jaffe and J. Sowers},
  journal={Diabetes},
  year={2013},
  volume={62},
  pages={313 - 319}
}
Two-thirds of adults in the U.S. are overweight or obese, and another 26 million have type 2 diabetes (T2D). Patients with diabetes and/or the metabolic syndrome have a significantly increased risk of heart attack and stroke compared with people with normal insulin sensitivity. Decreased insulin sensitivity in cardiovascular tissues as well as in traditional targets of insulin metabolic signaling, such as skeletal muscle, is an underlying abnormality in obesity, hypertension, and T2D. In the… Expand
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