Mineral evolution of bone.


A study on the evolution with age of the mineral composition of bones was performed on samples belonging to human and other common mammalian species (cattle, sheep, dog). The study was carried out on the ashes obtained by calcination of the bone samples (1 h at 900 degrees C). The calcined powders were carefully examined by X-ray diffraction, from which precise quantitative evaluation (also confirmed by chemical analysis) of the crystalline phases present was derived. These data were analysed as a function of the introduced fractional age phi, a new relative scale that allows even largely different lifespan species to be compared. An overall linear increase in (Ca + Mg)/P ratio with log phi was found and the other considerations on molecular constitution (especially as regards Mg2+ substituting for Ca2+ in very young subjects) of the various phases detected were formulated and relative implications evaluated. The results appear promising for an improvement of knowledge in the field of biomedical experimentation and clinical implantology.

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@article{Ravaglioli1996MineralEO, title={Mineral evolution of bone.}, author={Antonio Ravaglioli and Adriano Krajewski and Giancarlo Celotti and Alessandra Piancastelli and B Bacchini and Luciano Montanari and G Zama and L Piombi}, journal={Biomaterials}, year={1996}, volume={17 6}, pages={617-22} }