Mineral and matrix alterations in the bones of incisors-absent (ia/ia) osteopetrotic rats

@article{Boskey1985MineralAM,
  title={Mineral and matrix alterations in the bones of incisors-absent (ia/ia) osteopetrotic rats},
  author={Adele Ludin Boskey and Sandy C. Marks},
  journal={Calcified Tissue International},
  year={1985},
  volume={37},
  pages={287-292}
}
The bones of incisors-absent (ia/ia) osteopetrotic rats differ from those of their normal littermates (ia/+) in histologic and radiographic appearance and in mechanical properties. This study examined how the mineral and matrices of osteopetrotic metaphyses and calvaria differed from normal controls. Bones of 11-day-old and 52-day-old osteopetrotic animals had higher ash (mineral) contents that age-matched controls; osteopetrotic metaphyses had elevated hexosamine contents, indicative of the… CONTINUE READING

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