Mind your media.

@article{Lagziel2020MindYM,
  title={Mind your media.},
  author={Shoval Lagziel and Eyal Gottlieb and Tomer Shlomi},
  journal={Nature metabolism},
  year={2020}
}
A guide to interrogating immunometabolism
TLDR
This Review provides a framework for navigating and selecting the appropriate biochemical techniques to explore immunometabolism and highlights recent studies demonstrating the power of these metabolic approaches to uncover the role of metabolism in immunology. Expand
Challenges in Studying Stem Cell Metabolism.
TLDR
This review provides an examination of the methodologies used to characterize stem cell metabolism, highlighting their utility while placing a sharper focus on their limitations and hurdles the field needs to overcome for the optimal study of stem cell metabolic networks. Expand
Epithelial-mesenchymal transition is the main driver of intrinsic metabolism in cancer cell lines
TLDR
In absence of variations imposed by the microenvironment, the metabolism of cancer cell lines falls into only two major classes despite genetic heterogeneity, and a thorough integration of metabolic data with multiple omics data revealed a strong association with markers of epithelial-mesenchymal transition. Expand
Mechanometabolism: Mitochondria promote resilience under pressure
TLDR
It is revealed that extracellular matrix stiffness modulates mitochondrial shape and function and the mechanical reprogramming of mitochondria confers resistance to oxidative stress and promotes survival. Expand
Metabolic Plasticity Aids Amphotropism of Coxiella burnetii
TLDR
The study underscores that gluconeogenic capacity aids C. burnetii amphotropism and that the amphotropic nature of C.Burnetii should be considered when resolving virulence mechanisms in this pathogen. Expand
Metabolic Reprogramming of Cancer Cells during Tumor Progression and Metastasis
TLDR
This review summarizes the current understanding of metabolic reprogramming during cancer progression and metastasis, including cancer cell adaptation to the tumor microenvironment, defense against oxidative stress during anchorage-independent growth in vessels, and metabolic repprogramming during metastasis. Expand
Metabolic Vulnerabilities in Brain Cancer.
TLDR
An understanding of how both intrinsic and extrinsic factors modulate metabolism is becoming increasingly important for finding effect targets and therapeutics for GBM. Expand
Metabolic regulation of skeletal cell fate and function in physiology and disease
TLDR
Recent findings on the roles of cellular metabolism in determining skeletal stem cell fate, coordinating osteoblast and chondrocyte function, and organizing stromal support of haematopoiesis are discussed. Expand
The diversity and breadth of cancer cell fatty acid metabolism
TLDR
The complexity of cellular fatty acid metabolism in cancer, the various inputs and outputs of the intracellular free fatty acid pool, and the numerous ways that these pathways influence disease behavior are highlighted. Expand
The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells
TLDR
These results improve the understanding of serine metabolism in physiologically relevant nutrient conditions and allow us to predict interventions that may enhance the therapeutic response to dietary serine/glycine limitation. Expand
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