Corpus ID: 145454961

Mind games : the effects of diazepam on Evoked Potentials

@inproceedings{Jongsma2000MindG,
  title={Mind games : the effects of diazepam on Evoked Potentials},
  author={Marie-Louise Albertien Jongsma},
  year={2000}
}
The electroencephalogram (EEG) represents the electrical activity of the brain. Evoked Potentials (EPs) are small voltage fluctuations in the EEG resulting from sensory, cognitive or motor evoked neural activity. Variations in the EP waveform may be caused by several factors. 1. By employing different stimulation paradigms (which is studied in Part A of this thesis). By changes in the subject's state (which is studied in Part B of this thesis). 3. By psychoactive drugs (which is studied in this… Expand

Figures and Tables from this paper

The effects of diazepam on sensory gating in healthy volunteers
TLDR
P50 and P50 gating are indeed preattentive processes that are not controlled by diazepam, and this results contribute to the specificity of psychoactive drugs to control gating and demonstrate that this slow inhibitory process is not effected by this benzodiazepine. Expand
Repetition suppression of the rat auditory evoked potential at brief stimulus intervals
TLDR
The results found no evidence that rat AEP components show the reversal of repetition suppression at brief, relative to long, stimulus intervals as demonstrated for the N100 component in humans. Expand

References

SHOWING 1-10 OF 72 REFERENCES
Comparative frequency analysis of single EEG-evoked potential records.
TLDR
The gaps in earlier analysis on the relation between the amplitudes of EEG and EP components in various frequency channels could be determined in the time domain are filled with the further analysis of the EEG-EPograms simultaneously recorded from 5 different brain structures. Expand
Differential effects of non-REM and REM sleep on sensory gating in rats.
TLDR
Clear differences were seen in gating: compared to wakefulness a decrease was found during REM sleep while gating was unchanged during non-REM sleep while the latter outcome seems to confirm that gating in rats is indeed a preattentive process. Expand
Behavior-dependent and drug-induced changes of rat visual evoked potential: relation to the EEG spectral power.
TLDR
The neural activity of the occipital cortex is reflected in the VEP whereas the Occipital EEG possibly reflects the hippocampal activity in some behavioral states, which may be a reason for partly independent changes of VEP and EEG during different behavioral states and after application of neuroactive drugs. Expand
Effects of the anticonvulsant benzodiazepine clonazepam on event-related brain potentials in humans.
TLDR
The present result is compared with the pattern of ERP effects of the anticonvulsant carbamazepine that had been obtained using the same experimental paradigms, and the benzodiazepine clonazepam boosted the development of a distinct N2 which was not apparent in placebo subjects. Expand
Diazepam Effects on the P3 Event‐Related Potential
TLDR
Changes in P3 occurred in the absence of significant changes in the preceding evoked waves (N1, P2), and should be considered when the P3 is obtained for clinical or research purposes from medicated patients. Expand
Neuronal activities underlying the electroencephalogram and evoked potentials of sleeping and waking: Implications for information processing
  • A. Coenen
  • Medicine, Psychology
  • Neuroscience & Biobehavioral Reviews
  • 1995
TLDR
The notion of a general correspondence between thalamocortical neuronal activities and the polarity of transients in the cortical surface EEG, allows prudent speculations regarding components of ERPs. Expand
Event-related potentials in a passive and active auditory condition: effects of diazepam and buspirone on slow wave positivity
TLDR
It is suggested that cognitive processing of relevant stimuli is reduced by diazepam, Presumably, this is associated with the sedative effects of this drug. Expand
Late auditory evoked potentials: a method for monitoring drug effects on the central nervous system.
TLDR
An auditory event-related potential paradigm was designed to objectively quantify the effects of drugs on the central nervous system (CNS), and the amplitude of N1-P2 and the recovery of this complex across ISI appear to be rapid, reliable and sensitive measures of changes in brain function associated with drug intake. Expand
Effect of Midazolam on the Auditory Event‐Related Potential: Measures of Selective Attention
TLDR
Although routine clinical examination may be normal, full recovery from the effects of a typical intravenous dose of midazolam requires more than 50 min, and the potential for adverse drug interaction, particularly with narcotics, is still present at this time. Expand
P300 and traffic scenes: The effect of temazepam
TLDR
The present research investigated the effects of a minor tranquillizer (temazepam) on P300 in a paradigm that may be relevant for traffic behaviour and indicated that P300 amplitude increased with decreasing probability of the relevant stimulus and that P 300 was most pronounced at Pz. Expand
...
1
2
3
4
5
...