Mincle and human B cell function.

  title={Mincle and human B cell function.},
  author={Kazuhito Kawata and Petr Illarionov and Guo-xiang Yang and Thomas P. Kenny and Weici Zhang and Masanobu Tsuda and Yugo Ando and Patrick S. C. Leung and Aftab A Ansari and M Eric Gershwin},
  journal={Journal of autoimmunity},
  volume={39 4},
C-type lectin receptors are pattern recognition receptors that are critical for autoimmunity and the immune response. Mincle is a C-type lectin receptor expressed by a variety of antigen presenting cells including macrophages, neutrophils, dendritic cells and B cells; a variety of stimuli including stress are known to induce the expression of Mincle. Mincle is an FcRγ-associated activation receptor that senses damaged cells and upon ligation induces activated macrophages to produce inflammatory… CONTINUE READING