MinJ (YvjD) is a topological determinant of cell division in Bacillus subtilis.

@article{Patrick2008MinJI,
  title={MinJ (YvjD) is a topological determinant of cell division in Bacillus subtilis.},
  author={Joyce E. Patrick and Daniel B Kearns},
  journal={Molecular microbiology},
  year={2008},
  volume={70 5},
  pages={1166-79}
}
In Bacillus subtilis, FtsZ ring formation and cell division is favoured at the midcell because the inhibitor proteins MinC and MinD are indirectly restricted to the cell poles by the protein DivIVA. Here we identify MinJ, a topological determinant of medial FtsZ positioning that acts as an intermediary between DivIVA and MinD. Due to unrestricted MinD activity, cells mutated for minJ exhibited pleiotropic defects in homologous recombination, swarming motility and cell division. MinJ restricted… CONTINUE READING
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