Mimicking vernix caseosa--preparation and characterization of synthetic biofilms.

@article{Rissmann2009MimickingVC,
  title={Mimicking vernix caseosa--preparation and characterization of synthetic biofilms.},
  author={Robert Rissmann and Marion H. M. Oudshoorn and Raph{\"a}el Zwier and Maria Ponec and Joke A. Bouwstra and Wim E Hennink},
  journal={International journal of pharmaceutics},
  year={2009},
  volume={372 1-2},
  pages={59-65}
}
The multiple protecting and barrier-supporting properties of the creamy, white biofilm vernix caseosa (VC) before and after birth suggest that a VC biomimetic could be an innovative barrier cream for barrier-deficient skin. The aim of this study was the rational design and preparation of synthetic biofilms mimicking the unique composition and properties of natural VC. Hexagonal, highly hydrated hyperbranched polyglycerol microgel particles (30 microm in diameter) were embedded in a synthetic… CONTINUE READING