Miltefosine (Impavido): the first oral treatment against leishmaniasis

  title={Miltefosine (Impavido): the first oral treatment against leishmaniasis},
  author={Herbert Sindermann and Simon Croft and Kirsten Rita Engel and Wolfgang Bommer and Hans J Eibl and Claudia Unger and Juergen Engel},
  journal={Medical Microbiology and Immunology},
Miltefosine is a novel antileishmanial drug that has significant selectivity in both in vitro and in vivo models. Clinical efficacy was demonstrated for the treatment of visceral leishmaniasis with the advantage of oral administration over the currently recommended antileishmanial drugs that require parenteral administration. Miltefosine produces high cure rates also in patients resistant to the standard antimonial therapy. 
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