Milrinone modulates endotoxemia, systemic inflammation, and subsequent acute phase response after cardiopulmonary bypass (CPB).

@article{Mllhoff1999MilrinoneME,
  title={Milrinone modulates endotoxemia, systemic inflammation, and subsequent acute phase response after cardiopulmonary bypass (CPB).},
  author={Thomas M{\"o}llhoff and H. M. Loick and h c Hugo Van Aken and Christoph Stephan Schmidt and Norbert Rolf and Tony D T Tjan and Boulos Asfour and Elmar Berendes},
  journal={Anesthesiology},
  year={1999},
  volume={90 1},
  pages={72-80}
}
BACKGROUND Compromised splanchnic perfusion and the resulting intestinal mucosal injury leads to a decreased mucosal barrier function, which allows translocation of intestinal flora and endotoxemia. The authors evaluated the effects of milrinone on splanchnic oxygenation, systemic inflammation, and the subsequent acute-phase response in patients undergoing coronary artery bypass grafting. METHODS This open, placebo-controlled randomized clinical study enrolled 22 adult patients in two groups… CONTINUE READING

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