Milrinone for persistent pulmonary hypertension of the newborn.

@article{Bassler2010MilrinoneFP,
  title={Milrinone for persistent pulmonary hypertension of the newborn.},
  author={Dirk Bassler and Karen Kreutzer and Patrick McNamara and Haresh Kirpalani},
  journal={The Cochrane database of systematic reviews},
  year={2010},
  volume={11},
  pages={
          CD007802
        }
}
BACKGROUND Persistent pulmonary hypertension of the newborn (PPHN) is a clinical syndrome characterized by suboptimal oxygenation as a result of sustained elevation in pulmonary vascular resistance after birth. Currently, the therapeutic mainstay for PPHN is optimal lung inflation and selective vasodilatation with inhaled nitric oxide (iNO). However, iNO is not available in all countries and not all infants will respond to iNO. Milrinone is a phosphodiesterase III inhibitor which induces… CONTINUE READING

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