Milrinone, a new agent for the treatment of congestive heart failure.

The chemistry, pharmacology, pharmacokinetics, dosage, clinical efficacy, and adverse effects of milrinone are reviewed. Milrinone, which is structurally similar to amrinone, is an oral agent under investigation for the treatment of congestive heart failure. The drug produces positive inotropic and vasodilating effects through unknown mechanisms. Milrinone… CONTINUE READING