Military Blast-Related Traumatic Brain Injury

@article{Weppner2019MilitaryBT,
  title={Military Blast-Related Traumatic Brain Injury},
  author={Justin Weppner and Mark Linsenmeyer and William Ide},
  journal={Current Physical Medicine and Rehabilitation Reports},
  year={2019},
  volume={7},
  pages={323 - 332}
}
This paper aims to review and discuss the epidemiological, neuropathologic, and mechanistic characteristics of blast traumatic brain injury (bTBI) specific to the military population. Military service members have sustained over 383,000 reported incidents of TBI since 2000. In combat, mild bTBI due to explosive attacks comprise the most common type. Identification, treatment, and reporting of bTBI are compounded by the operational demands of combat as well as frequent co-presentation with PTSD… 
2 Citations
Development of a new militarily-relevant whole-body low-intensity blast model for mild and subconcussive traumatic brain injury: Examination of acute neurological and multi-organ pathological outcomes
TLDR
A newly developed experimental mouse model reproducing features of blast-induced neurotrauma (BINT), induced in operationally relevant manner using a compressed air-driven shock tube provides realistic representation of operational scenarios and reproduces militarily-relevant smBINT and rscBINT in the laboratory.
Cerebrospinal Fluid Cavitation as a Mechanism of Blast-Induced Traumatic Brain Injury: A Review of Current Debates, Methods, and Findings
TLDR
This review presents the most prominent debates on cavitation; how bubbles can form or exist within the cerebrospinal fluid and brain vasculature, potential mechanisms of cellular, and tissue level damage following the collapse of bubbles in response to local pressure fluctuations, and a survey of experimental and computational models used to address cavitation research questions.

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