Mild transcobalamin I (haptocorrin) deficiency and low serum cobalamin concentrations.

@article{Carmel2003MildTI,
  title={Mild transcobalamin I (haptocorrin) deficiency and low serum cobalamin concentrations.},
  author={Ralph Carmel},
  journal={Clinical chemistry},
  year={2003},
  volume={49 8},
  pages={
          1367-74
        }
}
BACKGROUND Low cobalamin concentrations are common, but their causes are often unknown. Transcobalamin I/haptocorrin (TC I/HC) deficiency, viewed as a rare cause, has not been examined systematically in patients with unexplained low serum cobalamin. METHODS Total TC I/HC was measured by RIA in three subgroups of 367, 160, and 38 patients with different categories of low cobalamin concentrations and three comparison subgroups of 112, 281, and 119 individuals with cobalamin concentrations… CONTINUE READING

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