Mild renal insufficiency is associated with increased cardiovascular mortality: The Hoorn Study.

  title={Mild renal insufficiency is associated with increased cardiovascular mortality: The Hoorn Study.},
  author={Ronald M. A. Henry and Piet J. Kostense and G J Klaasse Bos and Jacqueline M. Dekker and Giel Nijpels and R. Heine and L. M. Bouter and Coen D A Stehouwer},
  journal={Kidney international},
  volume={62 4},
BACKGROUND Cardiovascular mortality is extremely high in end-stage renal disease. Cardiovascular mortality risk also is increased in selected (high-risk) individuals with mild to moderate impairment of renal function. It is not clear whether a similar association exists in the general population and, if so, through what mechanisms. We investigated the association of renal function with all-cause and cardiovascular mortality in a population-based cohort and explored potential mechanisms… CONTINUE READING


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