Mild posttraumatic hypothermia reduces mortality after severe controlled cortical impact in rats.

@article{Clark1996MildPH,
  title={Mild posttraumatic hypothermia reduces mortality after severe controlled cortical impact in rats.},
  author={Robert B. Clark and Patrick M Kochanek and Donald W. Marion and Joanne K. Schiding and Mark Earl White and Alan M. Palmer and Steven DeKosky},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={1996},
  volume={16 2},
  pages={
          253-61
        }
}
The effect of posttraumatic hypothermia (brain temperature controlled at 32 degrees C for 4 h) on mortality after severe controlled cortical impact (CCI) was studied in rats. Four posttraumatic brain temperatures were compared: 37 degrees C (n = 10), 36 degrees C (n = 4), 32 degrees C (n = 10), and uncontrolled (UC; n = 6). Rats were anesthetized and subjected to severe CCI (4.0-m/s velocity, 3.0-mm depth) to the exposed left parietal cortex. At 10 min posttrauma the rats were cooled or… CONTINUE READING
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