Mild intraoperative hypothermia reduces production of reactive oxygen intermediates by polymorphonuclear leukocytes.

@article{Wenisch1996MildIH,
  title={Mild intraoperative hypothermia reduces production of reactive oxygen intermediates by polymorphonuclear leukocytes.},
  author={Christoph Wenisch and Edith Narzt and Daniel I Sessler and Berhard Parschalk and Rainer Lenhardt and Andrea Kurz and Wolfgang Graninger},
  journal={Anesthesia and analgesia},
  year={1996},
  volume={82 4},
  pages={
          810-6
        }
}
Mild hypothermia directly impairs numerous immune functions in vitro. However, the in vivo effects of mild hypothermia on neutrophil phagocytosis and oxidative killing remain unknown. We tested the hypothesis that mild intraoperative hypothermia decreases neutrophil phagocytic capacity and generation of reactive oxygen intermediates (a measure of oxidative killing). Additionally, we evaluated the effects of in vitro temperature manipulations on each function. Thermal management was randomly… CONTINUE READING

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