Mild dystrophic damage in the androgen-sensitive levator ani muscle of the mdx mouse.

@article{Souccar2005MildDD,
  title={Mild dystrophic damage in the androgen-sensitive levator ani muscle of the mdx mouse.},
  author={Caden Souccar and Maria Do Carmo Gonçalo and Hudson de Sousa Buck and Maria Teresa R. Lima-Landman and Ant{\^o}nio Jos{\'e} Lapa},
  journal={Neuromuscular disorders : NMD},
  year={2005},
  volume={15 1},
  pages={48-56}
}
The time course of muscular dystrophy on the androgen-sensitive levator ani muscle was compared to that of the diaphragm of dystrophic (mdx) mice aged 1-20 months. Muscle growth, isometric contractile properties and caffeine-induced contractures were determined to assess the hormone myotrophic effect, muscle strength and sarcoplasmic reticulum function, respectively, of both control and dystrophic muscles. Histological analysis of mdx muscles showed variable fiber size, centronucleated cells… CONTINUE READING