Mild arming and derivatization of natural products via an In(OTf)3-catalyzed arene iodination.

Abstract

Iodination of arene-containing natural products employing N-iodosuccinimide catalyzed by In(OTf)(3) at ambient temperature is reported as a versatile and mild method for natural product derivatization amenable to small scale. This process facilitates natural product derivatization of arene moieties for SAR studies, homo- and heterodimerization of natural… (More)
DOI: 10.1021/ol100587j

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