Mild and moderate hypothermia provide better protection than a burst-suppression dose of thiopental against ischemic spinal cord injury in rabbits.

@article{Matsumoto1997MildAM,
  title={Mild and moderate hypothermia provide better protection than a burst-suppression dose of thiopental against ischemic spinal cord injury in rabbits.},
  author={Masaki Matsumoto and Yasuhiko Iida and Takefumi Sakabe and Takehiro Sano and Teruhiko Ishikawa and Kazuhiko Nakakimura},
  journal={Anesthesiology},
  year={1997},
  volume={86 5},
  pages={
          1120-7
        }
}
BACKGROUND Controversy exists over the efficacy of different methods for protecting the spinal cord against experimental ischemic injury. Therefore, the authors compared the protective effects of thiopental with those of hypothermia (35 degrees C and 32 degrees C) on hindlimb motor functions and histopathology after transient spinal cord ischemia. METHODS Twenty-seven New Zealand white rabbits were assigned to one of the four groups: a thiopental-normothermia group (burst-suppression dose of… CONTINUE READING

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