Mild Hypoxia Enhances Proliferation and Multipotency of Human Neural Stem Cells

@inproceedings{Santilli2010MildHE,
  title={Mild Hypoxia Enhances Proliferation and Multipotency of Human Neural Stem Cells},
  author={Guido Santilli and Giuseppe Lamorte and Luigi Carlessi and Daniela Ferrari and Laura Rota Nodari and Elena Binda and Domenico Delia and Angelo L. Vescovi and Lidia de Filippis},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Neural stem cells (NSCs) represent an optimal tool for studies and therapy of neurodegenerative diseases. We recently established a v-myc immortalized human NSC (IhNSC) line, which retains stem properties comparable to parental cells. Oxygen concentration is one of the most crucial environmental conditions for cell proliferation and differentiation both in vitro and in vivo. In the central nervous system, physiological concentrations of oxygen range from 0.55 to 8% oxygen. In… CONTINUE READING
71 Citations
44 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 71 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 44 references

Similar Papers

Loading similar papers…