Mild Encephalitis with a Reversible Splenial Lesion: A Clinical Benign Condition, often Underrecognized – Clinical Case and Literature Review

Abstract

Mild encephalitis with reversible lesion in the splenium is a clinicoradiological syndrome characterized by a variegated symptomatology with a solitary mass in the central portion of the splenium of the corpus callosum. Complete spontaneous resolution is the hallmark of this syndrome, though its pathogenesis is still unknown. We describe the clinical picture of a 51-year-old woman who developed a partial sensitive seizure, with MRI evidence of a lesion localized in the posterior portion of the corpus callosum. The patient made a full recovery thanks to the administration of antiepileptic drugs. Acquiring knowledge of this syndrome, in the wide diagnostic panel which includes vertebrobasilar diseases besides the broad range of metabolic and electrolyte disorders, is crucial to a prompt clinical diagnosis and in establishing a reliable prognosis at an early stage.

DOI: 10.4103/0976-3147.203828

Cite this paper

@inproceedings{Marsala2017MildEW, title={Mild Encephalitis with a Reversible Splenial Lesion: A Clinical Benign Condition, often Underrecognized – Clinical Case and Literature Review}, author={Sandro Zambito Marsala and Eleonora Antichi and Michele Pistacchi and Manuela Gioulis and Rosa Maria Candeago and Roberta Taranto Montemurro and Manrico Gentile and Paolo D'Andrea and Franco Ferracci}, booktitle={Journal of neurosciences in rural practice}, year={2017} }