Migration rules: tumours are conglomerates of self-metastases

  title={Migration rules: tumours are conglomerates of self-metastases},
  author={Heiko Enderling and Lynn Hlatky and Philip Hahnfeldt},
  journal={British Journal of Cancer},
  pages={1917 - 1925}
Tumours are heterogeneous populations composed of different cells types: stem cells with the capacity for self-renewal and more differentiated cells lacking such ability. The overall growth behaviour of a developing neoplasm is determined largely by the combined kinetic interactions of these cells. By tracking the fate of individual cancer cells using agent-based methods in silico, we apply basic rules for cell proliferation, migration and cell death to show how these kinetic parameters… CONTINUE READING
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Brú I (2003) The universal dynamics of tumor growth

  • A Brú, S Albertos, J Luis Subiza, JL Garcı́a-Asenjo
  • Biophys J 85(5):
  • 2003
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