Migration of sea urchin primordial germ cells.

  title={Migration of sea urchin primordial germ cells.},
  author={Joseph P. Campanale and Tufan G{\"o}kirmak and J. J. Espinoza and Nathalie Oulhen and Gary M Wessel and Amro M Hamdoun},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  volume={243 7},
BACKGROUND Small micromeres are produced at the fifth cleavage of sea urchin development. They express markers of primordial germ cells (PGCs), and are required for the production of gametes. In most animals, PGCs migrate from sites of formation to the somatic gonad. Here, we investigated whether they also exhibit similar migratory behaviors using live-cell imaging of small micromere plasma membranes. RESULTS Early in gastrulation, small micromeres transition from non-motile epithelial cells… CONTINUE READING
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