Migration of polarized epithelial cells through permeable membrane substrates of defined pore size.

@article{Tucker1992MigrationOP,
  title={Migration of polarized epithelial cells through permeable membrane substrates of defined pore size.},
  author={Simon P Tucker and Lawrence R. Melsen and Richard W. Compans},
  journal={European journal of cell biology},
  year={1992},
  volume={58 2},
  pages={280-90}
}
We have observed that cells of various epithelial lines exhibit the ability to migrate through permeable membrane substrates containing 3.0 microns pores. Scanning and transmission electron microscopic observations of Vero C1008 and Caco-2 cell lines grown on polycarbonate membranes containing 3.0 microns pores revealed extensive penetration of the filter and the establishment of virtually complete monolayers on the opposing surface. The migration of MDCK cells was also observed to occur under… CONTINUE READING