Migration of human melanoma cells on hyaluronate is related to CD44 expression.

@article{Thomas1993MigrationOH,
  title={Migration of human melanoma cells on hyaluronate is related to CD44 expression.},
  author={Laurel Thomas and Tomomi Etoh and Ivan Stamenkovic and Martin C. Mihm and Hugh Randolph Byers},
  journal={The Journal of investigative dermatology},
  year={1993},
  volume={100 2},
  pages={115-20}
}
Phenotypic and functional aspects of melanoma-hyaluronate interactions were investigated by studying the expression of CD44, cell migration, and transmembrane penetration of human melanoma cell lines on hyaluronate-coated substrates. Expression of CD44 was tested by flow cytometry on seven human melanoma cell lines. Strong reactivity with anti-CD44 monoclonal antibody was observed in four of seven of the cell lines. Migration studies of CD44(+) cell lines on hyaluronic acid- and chondroitin-6… CONTINUE READING

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