Migration inhibition factor-like activity in inflammatory synovial fluids might be due to proteases.

@article{Geiger1976MigrationIF,
  title={Migration inhibition factor-like activity in inflammatory synovial fluids might be due to proteases.},
  author={Christian Geiger and Thomas L. Vischer},
  journal={Clinical and experimental immunology},
  year={1976},
  volume={26 1},
  pages={176-80}
}
Using an assay of macrophage migration, where the cells emigrate from an agarose droplet, it was found that the neutral proteases trypsin, chymotrypsin, Pronase and elastase have MIF-like activity. Appropriate enzyme inhibitors counteract this effect. To twelve synovial fluids from patients with inflammatory arthritis, which have MIF-like activity… CONTINUE READING