Migration and schizophrenia: meta-analysis and explanatory framework

@article{Henssler2019MigrationAS,
  title={Migration and schizophrenia: meta-analysis and explanatory framework},
  author={Jonathan Henssler and Lasse Brandt and Martin M{\"u}ller and Shuyan Liu and Christian Montag and Philipp Sterzer and Andreas Heinz},
  journal={European Archives of Psychiatry and Clinical Neuroscience},
  year={2019},
  volume={270},
  pages={325-335}
}
Systematic reviews and meta-analyses suggest that there are increased rates of schizophrenia and related psychoses in first- and second-generation migrants and refugees. Here, we present a meta-analysis on the incidence of non-affective psychotic disorders among first- and second-generation migrants. We found substantial evidence for an increased relative risk of incidence among first- and second-generation migrants compared to the native population. As heterogeneity of included studies was… 

Racism and psychosis: an umbrella review and qualitative analysis of the mental health consequences of racism

Qualitative and quantitative evidence is provided from a quantitative and qualitative analysis that the risk of poor mental health and psychotic experiences is related to racism associated with minority status and migration.

Risk of Psychosis Among Refugees: A Systematic Review and Meta-analysis.

Importance This systematic review and meta-analysis is, to date, the first and most comprehensive to focus on the incidence of non-affective psychoses among refugees. Objective To assess the

Traumatic Events, Social Adversity and Discrimination as Risk Factors for Psychosis - An Umbrella Review

Meta-analyses regarding trauma and social adversity observed that most significant social risk factors for psychosis were vulnerability for racist discrimination, migration, and childhood adversities, and social factors increasing the risk for psychosiswere variation/impairment of parental communication, aversive adult life events, bullying, and factors associated with social isolation and discrimination.

The effects of social isolation stress and discrimination on mental health

Evidence is synthesized that social separation stress, particularly in early life, activates the hypothalamic-pituitary-adrenal axis and interacts with monoaminergic, glutamatergic, and GABAergic neurotransmitter systems, inducing long-lasting reductions in serotonin turnover and alterations in dopamine receptor sensitivity.

Looking at Intergenerational Risk Factors in Schizophrenia Spectrum Disorders: New Frontiers for Early Vulnerability Identification?

A clinical-conceptual perspective is offered aimed to disentangle the complex intertwine of intergenerational risk factors that contribute to the risk of developing SMI in offspring, taking schizophrenia spectrum disorders as a paradigmatic example.

Migration and psychotic experiences in the Tokyo Teen Cohort

Treatment adherence to psychotropic drugs among non-Western migrants: a systematic review

There is a need for studies assessing the possible impact of interventions aiming at increasing adherence such as intercultural mediators and training of healthcare providers in cultural competencies.

Psycho-Socio-Economic Challenges of Internal Migrants of India: A Narrative Review and Recommendations for Integrative Model of Care

India needs to develop an integrated ‘rights-based approach’ for providing comprehensive care to migrants, including economic support, health care and active labour-market policy.

References

SHOWING 1-10 OF 101 REFERENCES

A meta-analysis of the risk for psychotic disorders among first- and second-generation immigrants

The increased risk of schizophrenia and related disorders among immigrants clearly persists into the second generation, suggesting that post-m migration factors play a more important role than pre-migration factors or migration per se.

Schizophrenia and migration: a meta-analysis and review.

Findings of previous studies implicating migration as a risk factor for the development of schizophrenia and a quantitative index of the associated effect size are synthesized to suggest a role for psychosocial adversity in the etiology of schizophrenia.

Incidence of psychotic disorders among first-generation immigrants and refugees in Ontario

The differential pattern of risk across ethnic subgroups in Ontario suggests that psychosocial and cultural factors associated with migration may contribute to the risk of psychotic disorders.

Urbanicity, social adversity and psychosis

It is unlikely that social drift alone can fully account for geographical variation in incidence of schizophrenia, and evidence suggests the impact of adverse social contexts – indexed by area‐level exposures such as population density, social fragmentation and deprivation – on risk of psychosis is explained.

The incidence of schizophrenia in European immigrants to Canada

Incidence of Schizophrenia or Other Psychoses in First- and Second-Generation Immigrants: A National Cohort Study

Having one parent born in Sweden had no protective effect on the risk of being hospitalized for psychotic disorders among second-generation immigrants, and the highest risks of psychotic disorders were found among first-generation and second- Generation Finns, after adjustment for socioeconomic status.

Increased rates of psychosis among immigrants to Sweden: is migration a risk factor for psychosis ?

Vulnerability to psychosis in immigrants may have been determined by factors other than the migration process, and background factors specifically associated with migration did not appear to contribute strongly to SLP in immigrants.

Refugee migration and risk of schizophrenia and other non-affective psychoses: cohort study of 1.3 million people in Sweden

Clinicians and health service planners in refugee receiving countries should be aware of a raised risk of psychosis in addition to other mental and physical health inequalities experienced by refugees.

Increased rates of schizophrenia among immigrants: some methodological concerns raised by Danish findings

While selective risk factors may be operating in various groups of immigrants, caution should be warranted in the interpretation of immigrant studies as large portions of transient visitors may obscure actual rates of mental disorders.

Risk of schizophrenia, schizoaffective, and bipolar disorders by migrant status, region of origin, and age-at-migration: a national cohort study of 1.8 million people

Increased risk of psychiatric disorders associated with migration and minority status may be specific to psychotic disorders, with exact risk dependent on the region of origin.
...