Migration and invasion of oral squamous carcinoma cells is promoted by WNT5A, a regulator of cancer progression.

@article{Prgomet2015MigrationAI,
  title={Migration and invasion of oral squamous carcinoma cells is promoted by WNT5A, a regulator of cancer progression.},
  author={Zdenka Prgomet and Lena Axelsson and Pia Lindberg and Tommy Andersson},
  journal={Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology},
  year={2015},
  volume={44 10},
  pages={
          776-84
        }
}
BACKGROUND Oral squamous cell carcinoma (OSCC) constitutes 90% of all cancers in the oral cavity, and the prognosis for patients diagnosed with OSCC is still poor. The identification of novel therapeutic targets and prognostic markers for OSCC is therefore essential. Previous studies of OSCC revealed an increased expression of WNT5A in the tumor tissue. However, no functional studies of WNT5A-induced effects in OSCC have been performed. METHODS Two different OSCC cell lines were used for… CONTINUE READING
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