Migration and invasion in brain neoplasms.

  title={Migration and invasion in brain neoplasms.},
  author={Anna J Bolteus and Michael E. Berens and Geoffrey J. Pilkington},
  journal={Current neurology and neuroscience reports},
  volume={1 3},
Local invasion of the brain by neoplastic glial cells is a major obstacle to effective treatment of intrinsic brain tumors. Invasion is directly related to histologic malignancy, but occurs to some extent irrespective of tumor grade. Because the brain-to-tumor interface is not well demarcated, total surgical removal is rarely possible; moreover, as invading… CONTINUE READING