Migration and differentiation of Langerhans cell precursors.

  title={Migration and differentiation of Langerhans cell precursors.},
  author={Kristine Kohl and Elisabeth Klein and Susanne Koch and Sylvia Schnautz and Thomas Bieber},
  journal={European journal of cell biology},
  volume={83 11-12},
Epidermal Langerhans cells (LC) are the first sentinels of the skin immune system. To study immigration of human LC precursor cells into the skin, we established a two-compartmental skin model consisting of a dermal matrix and an epidermal sheet of keratinocytes. We tested the individual components of the skin model for their influence on phenotype and… CONTINUE READING