Migration, integration and maturation of photoreceptor precursors following transplantation in the mouse retina.

@article{WarreCornish2014MigrationIA,
  title={Migration, integration and maturation of photoreceptor precursors following transplantation in the mouse retina.},
  author={Katherine Warre-Cornish and Amanda C. Barber and Jane C. Sowden and Robin R Ali and R. M. Akers R. E. Pearson},
  journal={Stem cells and development},
  year={2014},
  volume={23 9},
  pages={941-54}
}
Retinal degeneration leading to loss of photoreceptors is a major cause of untreatable blindness. Recent research has yielded definitive evidence for restoration of vision following the transplantation of rod photoreceptors in murine models of blindness, while advances in stem cell biology have enabled the generation of transplantable photoreceptors from embryonic stem cells. Importantly, the amount of visual function restored is dependent upon the number of photoreceptors that migrate… CONTINUE READING

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