author={Messoud Ashina},
  journal={The New England journal of medicine},
  volume={383 19},
  • M. Ashina
  • Published 5 November 2020
  • Medicine
  • The New England journal of medicine

Exercise interventions in migraine patients: a YouTube content analysis study based on grades of recommendation

Background Migraine is the second leading cause of disability worldwide, engendering a high economic cost in developed countries. The adverse events related to pharmacological treatment use have

Proteomic and metabolomic profiling of acupuncture for migraine reveals a correlative link via energy metabolism

Treatment of migraine with acupuncture was associated with significant changes in key molecules and pathways, indicative of physiological changes in the trigeminovascular system, glutamate neurotoxicity, and other migraine-related physiological changes.

Immunologic aspects of migraine: A review of literature

The immunological aspects of migraine, which includes mast cells, immunoglobulin E, histamine, and cytokines, are summarized to suggest that blocking these pathways using immunologic agents such as CGRP antibody, anti-CGRP receptor antibody, and interleukin-1 beta (IL-1β)/interleuk in 1 receptor type 1 (IL -1R1) axis-related agents may be promising as potential prophylactic migraine treatments.

Dietary ω-3 intake for the treatment of morning headache: A randomized controlled trial

Evidence of a positive impact of ω-3-enriched MMD regimen on the inflammatory status and MH is provided, providing evidence of apositive impact of omega-3 (ω-3) intake in a Modified Mediterranean Diet.

Altered static functional network connectivity predicts the efficacy of non-steroidal anti-inflammatory drugs in migraineurs without aura

Brain networks have significant implications for the understanding of migraine pathophysiology and prognosis. This study aimed to investigate whether large-scale network dysfunction in patients with

Relationships among Symptoms, Disability, Type D Personality, and Quality of Life in Patients with Migraine: A Cross-Sectional Study in South Korea.

Higher Circulating Vitamin D Levels Are Associated With Decreased Migraine Risk: A Mendelian Randomization Study

This two-sample MR study showed genetically determined increased circulating vitamin D levels are associated with decreased migraine risk, which seems consistent across different migraine subtypes.

Neurological mechanism and treatment effects prediction of acupuncture on migraine without aura: Study protocol for a randomized controlled trial

It is hypothesized that acupuncture therapy may treat MWoA by restoring the neuropathological alterations in brain activity and should provide valuable scientific proof for the effects of acupuncture and demonstrate the usefulness of acupuncture in the treatment ofMWoA.

Targeting enkephalins and pituitary adenylate cyclase-activating polypeptide (PACAP) in migraine

  • M. Ashina
  • Biology, Psychology
    Brain : a journal of neurology
  • 2022
Both studies provide new data supporting the possible use of delta opioid agonists and anti-PACAP drugs in migraine treatment and show that a non-selective K ATP channel inhibitor glibenclamide partially inhibited PACAP-38-induced hypersensitivity.