Migraine prevention with a supraorbital transcutaneous stimulator

  title={Migraine prevention with a supraorbital transcutaneous stimulator},
  author={Jean Schoenen and Bart Vandersmissen and Sandrine Jeangette and Luc Herroelen and Michel Vandenheede and Pascale G{\'e}rard and Delphine Magis},
  pages={697 - 704}
Objective: To assess efficacy and safety of trigeminal neurostimulation with a supraorbital transcutaneous stimulator (Cefaly, STX-Med., Herstal, Belgium) in migraine prevention. Methods: This was a double-blinded, randomized, sham-controlled trial conducted at 5 Belgian tertiary headache clinics. After a 1-month run-in, patients with at least 2 migraine attacks/month were randomized 1:1 to verum or sham stimulation, and applied the stimulator daily for 20 minutes during 3 months. Primary… 

Figures and Tables from this paper

Migraine prevention with a supraorbital transcutaneous stimulator: A randomized controlled trial

It is proposed that acupuncture can predict the efficacy of STS: if acupuncture is effective, STS will also be effective and worth performing.

Transcutaneous Supraorbital Stimulation as a Preventive Treatment for Chronic Migraine: A Prospective, Open-Label Study.

Noninvasive, transcutaneous supraorbital nerve stimulation could hold preventive properties in the treatment of CM, but the effect may be either mild or controversial.

Migraine Prevention Using Different Frequencies of Transcutaneous Occipital Nerve Stimulation: A Randomized Controlled Trial.

Effectiveness of transcutaneous electrical nerve stimulation for the treatment of migraine: a meta-analysis of randomized controlled trials

This meta-analysis suggests that TENS may serve as an effective and well-tolerated alternative for migraineurs, however, low quality of evidence prevents us from reaching definitive conclusions.

Acute migraine therapy with external trigeminal neurostimulation (ACME): A randomized controlled trial

One-hour treatment with external trigeminal nerve stimulation resulted in significant headache pain relief compared to sham stimulation and was well tolerated, suggesting it may be a safe and effective acute treatment for migraine attacks.

Noninvasive vagus nerve stimulation as acute therapy for migraine

This randomized sham-controlled trial supports the abortive efficacy of nVNS as early as 30 minutes and up to 60 minutes after an attack and suggest effective pain relief, tolerability, and practicality of n VNS for the acute treatment of episodic migraine.

Greater occipital and supraorbital nerve blockade for the preventive treatment of migraine: a single-blind, randomized, placebo-controlled study

The results suggest that GON and SON blockade with lidocaine was more effective than the placebo in the prophylactic treatment of both episodic and chronic migraine.

The influence of ictal cutaneous allodynia on the response to occipital transcutaneous electrical stimulation in chronic migraine and chronic tension-type headache: A randomized, sham-controlled study

Severe CA is associated with decreased response to treatment with OTES in patients with CM and CTTH, and the number of headache-free days per month was significantly reduced in the real but not in the sham group.



Supraorbital transcutaneous neurostimulation has sedative effects in healthy subjects

Supraorbital high frequency TNS applied with the Cefaly® device decreases vigilance in healthy volunteers, which opens interesting perspectives for the treatment of hyperarousal states and, possibly, insomnia.

Central neuromodulation in chronic migraine patients with suboccipital stimulators: a PET study.

The activation pattern in the dorsal rostral pons is highly suggestive of a role for this structure in the pathophysiology of chronic migraine and the localization and persistence of activity during stimulation is exactly consistent with a region activated in episodic migraine, and with the persistence of activation of that area after successful treatment.

Occipital nerve stimulation for the treatment of intractable chronic migraine headache: ONSTIM feasibility study

The results of this feasibility study offer promise and should prompt further controlled studies of occipital nerve stimulation (ONS) in CM.

Topiramate in migraine prevention: results of a large controlled trial.

Topiramate, 100 or 200 mg/d, was effective as a preventive therapy for patients with migraine and eliminated paresthesia, fatigue, nausea, anorexia, and taste per version.

Topiramate for migraine prevention: a randomized controlled trial.

Topiramate showed significant efficacy in migraine prevention within the first month of treatment, an effect maintained for the duration of the double-blind phase.

Combined occipital and supraorbital neurostimulation for the treatment of chronic migraine headaches: Initial experience

Combined occipital nerve–supraorbital nerve neurostimulation systems may provide effective treatment for patients with chronic migraine and refractory chronic migraine headaches.

Transcutaneous electrical stimulation.

  • W. Bauer
  • Medicine
    Archives of otolaryngology--head & neck surgery
  • 1986
To the Editor .—I was pleased to read that Dr Dobie has explored electrical tinnitus suppression, as reported in the July 1986 issue of theArchives, 1 but his success rate was extremely poor and

Anticonvulsants in Migraine Prophylaxis: A Cochrane Review

Anticonvulsants, considered as a class, reduce migraine frequency by about 1.3 attacks per 28 days compared with placebo, and more than double the number of patients for whom migraine frequency is reduced by ≥50% relative to placebo.