Migraine and stroke: a complex association with clinical implications

@article{Kurth2012MigraineAS,
  title={Migraine and stroke: a complex association with clinical implications},
  author={Tobias Kurth and Hugues Chabriat and Marie Germaine Bousser},
  journal={The Lancet Neurology},
  year={2012},
  volume={11},
  pages={92-100}
}
Migraine, Ischemic Stroke and
Migraine and risk of stroke
TLDR
It is found that ischaemic stroke in people with migraine is strongly associated with migraine with aura, young age, female sex, use of oral contraceptives and smoking habits, and the mechanism behind the migraine-stroke association is unknown.
Migraine and stroke: In search of shared mechanisms
TLDR
An extended literature review of experimental and clinical evidence supporting the association between migraine and ischemic stroke and proposes mechanistic hypotheses to explain the link, such as microembolic triggers of migraine and enhanced sensitivity to isChemic injury in migraineurs.
Migraine and Stroke: A Continuum of Association in Adults
TLDR
Migraine and stroke are the most common neurovascular disorders affecting adults and migraine may be viewed as a potentially modifiable risk factor for stroke.
Cerebrovascular Disease and Migraine
The Association of Cardiovascular Disease and Migraine: Review
TLDR
A review article will discuss the association between migraine headache and certain cardiovascular disorders, and the risks of arrhythmia and mitral valve prolapse have been found to be different from normal population.
Stroke and Migraine
Migraine is a marker for risk of both ischaemic and haemorrhagic stroke
  • T. Kurth
  • Medicine, Psychology
    Evidence-Based Medicine
  • 2014
Commentary on: Sacco S, Ornello R, Ripa P, et al. Migraine and hemorrhagic stroke: a meta-analysis. Stroke 2013;44:3032–8.[OpenUrl][1][Abstract/FREE Full Text][2] Migraine is one of the most common
Migraine and the risk of stroke.
  • R. Dafer
  • Medicine, Psychology
    Disease-a-month : DM
  • 2015
Migraine and Stroke: “Vascular” Comorbidity
TLDR
Current evidence supports a clinical management where MA patients should be screened for other concomitant vascular risk factors and treated accordingly, and there still remains the question as to whether migraine should be considered a true “vascular disease” or if the comorbidity between migraine and cerebrov vascular disease may have underlying shared risk factors or pathophysiological mechanisms.
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References

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Relation between migraine and stroke
Coagulation abnormalities in migraine and ischaemic cerebrovascular disease: a link between migraine and ischaemic stroke?
TLDR
Findings suggest a higher frequency of some genetic abnormalities in migraine with aura patients and persistent hypercoagulability may explain the tendency for these patients to develop thromboembolic cerebrovascular events, especially when they are exposed to additional procoagulate stresses.
Migraine and cardiovascular disease
TLDR
Increased vigilance is recommended for modifiable cardiovascular risk factors in migraineurs, especially with MA, and it will be important to determine whether MA is a modifiable risk factor for CVD and if preventive medications for migraine or antiplatelet therapy might reduce the risk of CVD in patients with MA.
Probable Migraine With Visual Aura and Risk of Ischemic Stroke: The Stroke Prevention in Young Women Study
TLDR
PMVA was associated with an increased risk of stroke, particularly among women without other medical conditions associated with stroke, and Behavioral risk factors, specifically smoking and oral contraceptive use, markedly increased the risk of PMVA, as did recent onset ofPMVA.
Ischaemia-induced (symptomatic) migraine attacks may be more frequent than migraine-induced ischaemic insults.
TLDR
It seems that ischaemia-induced migraine attacks may be more frequent than migraine-induced ischaemic insults, and migraine is not as strong a risk factor for stroke as indicated by the mere coincidence of the two disorders.
A controlled study of ischemic stroke risk in migraine patients.
Migraine and Functional Outcome From Ischemic Cerebral Events in Women
TLDR
Results of this large prospective cohort suggest that women with migraine with aura are at increased risk of experiencing TIA or ischemic stroke with good functional outcome.
Migraine and risk of cardiovascular disease in women.
TLDR
In this large, prospective cohort of women, active migraine with aura was associated with increased risk of major CVD, myocardial infarction, ischemic stroke, and death due to isChemic CVD as well as with coronary revascularization and angina.
Duration, frequency, recency, and type of migraine and the risk of ischaemic stroke in women of childbearing age
TLDR
The data support earlier reports of a relation between ischaemic stroke and migraine with aura, and the risk seems particularly high in those whose initial migraine type involved aura occurring more than 12 times per year.
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