Migraine and percutaneous patent foramen ovale closure: a systematic review and meta-analysis

@inproceedings{Shi2017MigraineAP,
  title={Migraine and percutaneous patent foramen ovale closure: a systematic review and meta-analysis},
  author={Yu-jie Shi and Jun Lv and Xing-Ting Han and Guogang Luo},
  booktitle={BMC cardiovascular disorders},
  year={2017}
}
BACKGROUND The association between patent foramen ovale (PFO) and migraine with aura (MA) is well established. However, the benefits of PFO closure are less certain in patients with migraine without aura (MwoA). METHODS We systematically searched Pubmed for pertinent clinical studies published from January 2000 to July 2015. The primary end-point was the elimination or significant improvement of migraine symptoms after PFO closure. RESULTS Upon screening an initial list of 315 publications… CONTINUE READING