Migfilin sensitizes cisplatin-induced apoptosis in human glioma cells in vitro

@inproceedings{Fan2012MigfilinSC,
  title={Migfilin sensitizes cisplatin-induced apoptosis in human glioma cells in vitro},
  author={Jing Fan and Yun-wei Ou and Chuan-yue Wu and Chun-jiang Yu and Yong-mei Song and Qimin Zhan},
  booktitle={Acta Pharmacologica Sinica},
  year={2012}
}
Aim:Filamin binding LIM protein 1, also known as migfilin, is a skeleton organization protein that binds to mitogen-inducible gene 2 at cell-extracellular matrix adhesions. The aim of this study was to investigate the role of migfilin in cisplatin-induced apoptosis in human glioma cells, to determine the functional domains of migfilin, and to elucidate the… CONTINUE READING