Mifepristone With Buccal Misoprostol for Medical Abortion: A Systematic Review

@article{Chen2015MifepristoneWB,
  title={Mifepristone With Buccal Misoprostol for Medical Abortion: A Systematic Review},
  author={Melissa J. Chen and M. Creinin},
  journal={Obstetrics \& Gynecology},
  year={2015},
  volume={126},
  pages={12–21}
}
OBJECTIVE: To summarize clinical outcomes and adverse effects of medical abortion regimens consisting of mifepristone followed by buccal misoprostol in pregnancies through 70 days of gestation. DATA SOURCES: We used PubMed, ClinicalTrials.gov, and reference lists from published reports to identify relevant studies published between November 2005 and January 2015 using the search terms “mifepristone and medical abortion” and “buccal and misoprostol.” METHODS OF STUDY SELECTION: Studies were… Expand

Paper Mentions

Interventional Clinical Trial
The purpose of this study is to assess the effectiveness, safety, and acceptability of home-administered medical abortion at gestational age of 8 to ≤9 weeks versus >9 to ≤12 weeks… Expand
ConditionsMedical Abortion
InterventionDrug
Outcomes During Early Implementation of Mifepristone-Buccal Misoprostol Abortions up to 63 Days of Gestation in a Canadian Clinical Setting.
Acceptability and feasibility of outpatient medical abortion with mifepristone and misoprostol up to 70 days gestation in Singapore.
Pain during medical abortion: a multicenter study in France.
Outpatient medical abortion is safe and effective through 70 days gestation.
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References

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Two Distinct Oral Routes of Misoprostol in Mifepristone Medical Abortion: A Randomized Controlled Trial
Comparing two early medical abortion regimens: mifepristone+misoprostol vs. misoprostol alone.
Mifepristone followed by home administration of buccal misoprostol for medical abortion up to 70 days of amenorrhoea in a general practice in Curaçao
Extending Outpatient Medical Abortion Services Through 70 Days of Gestational Age
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