Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer

Abstract

Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria. BNIP3 and NIX are critical mediators for the Mieap-regulated mitochondrial quality control. Mieap suppresses murine intestinal tumor via its mitochondrial quality control function. To explore the role of the Mieap-regulated mitochondria quality… (More)
DOI: 10.1038/oncsis.2015.43

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Cite this paper

@inproceedings{Kamino2016MieapregulatedMQ, title={Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer}, author={Hiroki Kamino and Yasuhiro Nakamura and Masayuki Tsuneki and Hitomi Sano and Youji Miyamoto and Nobuo Kitamura and Manabu Futamura and Yoshikatsu Kanai and Hiroki Taniguchi and Dai Shida and Yoshihiro Kanemitsu and Yoshihiro Moriya and K Yoshida and Hatsuko Arakawa}, booktitle={Oncogenesis}, year={2016} }